I have designed websites and used flash Dreamweaver and frontpage, I am now going to venture into MySQL, is their Wysiwyg, or is there a really user-friendly program, all my data is I excel spreadsheets
What program is best for the creation and editing of MySQL?
I think you have a misconception about MySQL. It's a relational database. You should first learn how to design a database and some SQL. There are a couple of GUI tools (free) for download at the MySQL site. These tools are designed to make the work of the DBA or developer easier but they still require that you know how the underlying database works.
Personally, i use PHPMyadmin together with a compatible compiler like Visual Studio.
I would recommend you use PHPMyadmin for MySQL administration combined with your prefered compiler like Dreamweaver.